version: 1
defaults:
  method: mckinsey_market

methods:
  mckinsey_market:
    name: McKinsey-style market and strategy research
    best_for:
      - market research
      - investment memo
      - competitive landscape
    structure_principle: Pyramid principle with MECE chapter coverage.
    task_axes:
      - literature
      - regulatory
      - patents
      - market
      - counter
    integrated_lanes:
      - literature evidence
      - regulatory pathway
      - patent/IP position
      - market and competitor evidence
      - counter-evidence and uncertainty
    framework_sections:
      - central_thesis
      - chapter_outline
      - alternative_frameworks
      - risks_and_dependencies

  gmp_gap_assessment:
    name: GMP consulting gap assessment and remediation
    best_for:
      - GMP audit remediation
      - quality system consulting
      - supplier audit CAPA
    structure_principle: Regulation-to-gap-to-risk-to-CAPA pathway.
    task_axes:
      - regulatory_gap
      - risk_classification
      - capa_design
      - ownership_timeline
      - verification_evidence
      - counter
    framework_sections:
      - regulatory_baseline
      - gap_matrix
      - risk_ranking
      - capa_roadmap
      - verification_plan

  cmc_process_risk:
    name: CMC process and scale-up risk assessment
    best_for:
      - process development
      - tech transfer
      - manufacturing readiness
    structure_principle: Process-flow, CQA/CPP, scale-up, control strategy.
    task_axes:
      - process_flow
      - cqa_cpp
      - scale_up_risk
      - control_strategy
      - supply_chain
      - counter
    framework_sections:
      - process_map
      - critical_quality_attributes
      - critical_process_parameters
      - scale_up_risks
      - control_strategy

  rd_go_no_go:
    name: R&D go/no-go decision research
    best_for:
      - project initiation
      - modality selection
      - development strategy
    structure_principle: Scientific rationale, proof-of-concept, IP/FTO, development path, go/no-go criteria.
    task_axes:
      - scientific_rationale
      - poc_evidence
      - ip_fto
      - development_path
      - commercial_window
      - counter
    framework_sections:
      - scientific_rationale
      - evidence_threshold
      - ip_fto
      - development_plan
      - go_no_go_criteria

  management_consulting:
    name: Management consulting diagnostic and operating model
    best_for:
      - organization diagnosis
      - operating model design
      - governance and process improvement
    structure_principle: Diagnostic baseline, capability gaps, operating model, roadmap, governance.
    task_axes:
      - current_state
      - capability_gap
      - operating_model
      - governance
      - implementation_roadmap
      - counter
    framework_sections:
      - current_state_diagnosis
      - capability_gap
      - future_state_model
      - roadmap
      - governance_metrics

  gmp_quality_operations_diagnosis:
    name: GMP quality, manufacturing process, and operations diagnosis
    best_for:
      - GMP audit remediation from client materials
      - quality system diagnosis
      - manufacturing process system diagnosis
      - operations management transformation
    structure_principle: Start from site audit evidence, map findings to regulatory baseline and operating model gaps, then design short/mid/long-term remediation.
    task_axes:
      - input_material_findings
      - nmpa_fda_ema_ich_who_baseline
      - quality_system_gap
      - manufacturing_process_risk
      - operations_management_gap
      - team_capability
      - capa_roadmap
      - verification_evidence
      - counter
    integrated_lanes:
      - site audit and recap findings
      - official regulatory and guideline baseline
      - enforcement precedents and warning letters
      - quality/manufacturing/operations gap analysis
      - remediation actions, ownership, verification evidence
      - counter-evidence and boundary conditions
    framework_sections:
      - material_evidence_map
      - regulatory_and_best_practice_baseline
      - quality_system_gap_matrix
      - manufacturing_process_risk_map
      - operations_management_diagnosis
      - people_and_capability_diagnosis
      - short_mid_long_term_roadmap
      - governance_and_verification_plan
