{
  "2'-F-CTP": "2'-F-CTP",
  "2'-F-UTP": "2'-F-UTP",
  "2'-OMe-ATP": "2'-OMe-ATP",
  "2'-OMe-UTP": "2'-OMe-UTP",
  "2'-acetal levulinic ester (ALE) phosphoramidite": "2'-缩醛乙酰丙酸酯（ALE）亚磷酰胺",
  "32P-end-labeling": "32P末端标记",
  "500 Å pore": "500 Å孔径",
  "AGT": "AGT",
  "AJIPHASE®": "AJIPHASE®",
  "ANGPTL3": "ANGPTL3",
  "AOF formulation": "无动物及人源成分（AOF）配方",
  "API sameness": "API同一性",
  "APOC3": "APOC3",
  "ASCVD": "动脉粥样硬化性心血管疾病",
  "ASGPR": "去唾液酸糖蛋白受体",
  "ASMF": "ASMF备案",
  "Adaptive Laboratory Evolution": "适应性实验室进化",
  "Ajinomoto Bio-Pharma Services": "味之素生物制药服务",
  "Ajinomoto OmniChem": "Ajinomoto OmniChem",
  "Amide linker": "酰胺接头",
  "Angiotensinogen": "血管紧张素原",
  "Antibody-Drug Conjugate": "抗体偶联药物",
  "BD value": "BD交易价值",
  "BIOSECURE Act": "《生物安全法案》",
  "BTT activation": "BTT活化",
  "Bachem": "Bachem",
  "BeBetter Med": "必贝特",
  "Beyotime": "碧云天",
  "Biologics License Application": "生物制品上市许可申请",
  "Biomaide": "博迈德",
  "BirA/AviTag": "BirA/AviTag",
  "Bis-RNAi": "Bis-RNAi",
  "C5": "C5",
  "CDE": "药品审评中心",
  "CDMO": "合同开发与生产组织",
  "CID fragmentation": "碰撞诱导解离（CID）碎裂",
  "CLEA-LentiKats lipase formulation": "CLEA-LentiKats脂肪酶制剂",
  "CMC development timeline": "CMC开发周期",
  "CPG support": "CPG载体",
  "CTA": "临床试验申请",
  "Calantha™": "Calantha™",
  "Calf Intestinal Alkaline Phosphatase": "小牛肠碱性磷酸酶",
  "Candida antarctica lipase B": "南极假丝酵母脂肪酶B",
  "Category I": "第I类",
  "Category II": "第II类",
  "Category III": "第III类",
  "Category IV": "第IV类",
  "ChemGenes": "ChemGenes",
  "Chinese IND": "中国IND",
  "Class 3": "第3类",
  "Complement Factor B": "补体因子B",
  "Complete Response Letter": "完全答复函",
  "Controlled pore glass": "受控孔径玻璃",
  "Cross-Linked Enzyme Aggregates": "交联酶聚集体",
  "CuAAC": "铜催化叠氮-炔烃环加成",
  "D-galactosamine": "D-半乳糖胺",
  "DBCO": "二苯并环辛炔（DBCO）",
  "DMF": "DMF备案",
  "DMT-on HPLC purification handle": "DMT-on HPLC纯化把手",
  "DNase I": "DNase I",
  "Deep Eutectic Solvent": "深共熔溶剂",
  "Dibenzocyclooctyne": "二苯并环辛炔",
  "Dual-Target RNAi Drug": "双靶点RNAi药物",
  "ECO GMP Manufacturing Center": "ECO GMP生产中心",
  "ECO Synthesis platform": "ECO Synthesis平台",
  "ECO ligase": "ECO连接酶",
  "FDA/CDER": "FDA/CDER",
  "Factor XI": "凝血因子XI",
  "Fall Line Endurance Fund": "Fall Line Endurance Fund",
  "Full-Length Product": "全长产物",
  "G5 GalNAc support": "G5 GalNAc载体",
  "G5 ribofuranose": "G5核糖呋喃糖",
  "GDOC": "GDOC平台",
  "GDOC platform": "GDOC平台",
  "GEMINI™": "GEMINI™平台",
  "GMP-grade QC enzyme panel": "GMP级质控酶组合",
  "GT-multi-siRNA": "GT-multi-siRNA",
  "GalAhead": "GalAhead™",
  "GalNAc-PA": "GalNAc-亚磷酰胺（GalNAc-PA）",
  "GalNAc-siRNA": "GalNAc-siRNA",
  "GalT": "GalT",
  "GnTI": "GnTI",
  "GreenLight Biosciences": "GreenLight Biosciences",
  "H1 subunit": "H1亚基",
  "H2 subunit": "H2亚基",
  "Hongene": "兆维",
  "Host-Cell Protein": "宿主细胞蛋白",
  "Huntingtin": "亨廷顿蛋白",
  "Hydroxyprolinol scaffold": "羟脯氨醇（tHP）骨架",
  "ICH Q11 Q&A": "ICH Q11问答",
  "ICH Q13": "ICH Q13",
  "ICH Q2(R1)": "ICH Q2(R1)",
  "ICH Q3D(R2)": "ICH Q3D(R2)",
  "ICP-MS": "ICP-MS",
  "IND-to-dosing gap": "IND获批与首次给药时间差",
  "IVT": "体外转录",
  "Just Climate": "Just Climate",
  "Kd": "Kd值",
  "Kinovate Life Sciences": "Kinovate Life Sciences",
  "L96 ligand": "L96配体",
  "LDL-C": "LDL-C",
  "LGC Biosearch Technologies": "LGC Biosearch Technologies",
  "Leloir glycosyltransferases": "Leloir糖基转移酶",
  "Locked Nucleic Acid": "锁核酸",
  "Lp(a)": "Lp(a)",
  "ManII": "ManII",
  "Maywavee": "迈威生物",
  "MutS Homolog 3": "MutS同源物3",
  "N-acetylgalactosamine": "N-乙酰半乳糖胺",
  "NAG37": "NAG37",
  "NDA": "新药申请",
  "NMPA": "国家药品监督管理局",
  "Nitto Denko Avecia": "Nitto Denko Avecia",
  "NittoPhase HL": "NittoPhase HL",
  "Norroa": "Norroa",
  "Notice No. 21 of 2026": "2026年第21号通告",
  "Nuclease P1": "核酸酶P1",
  "Nucleoside Triphosphate": "核苷三磷酸",
  "OPR&D": "《有机工艺研究与开发》（OPR&D）",
  "PCSK9": "PCSK9",
  "PDE": "允许日暴露量",
  "PMO synthesis": "PMO合成",
  "PVA entrapment": "PVA包埋",
  "Phosphodiester linker": "磷酸二酯接头",
  "Polynucleotide Kinase (T4)": "多核苷酸激酶（T4）",
  "Poresyn Solutions": "Poresyn Solutions",
  "Prime Synthesis CPG": "Prime Synthesis CPG",
  "PrimeMax siRNA CPG": "PrimeMax siRNA CPG",
  "Process Analytical Technology": "过程分析技术",
  "Process Atlas": "工艺图谱",
  "Process Mass Intensity": "工艺质量强度",
  "Q3M": "Q3M",
  "Q6M": "Q6M",
  "QC biocatalyst": "质控生物催化剂",
  "RADS™": "RADS™",
  "RNA interference": "RNA干扰",
  "RNA-Induced Silencing Complex": "RNA诱导沉默复合体",
  "RNase A": "核糖核酸酶A",
  "RNase H": "核糖核酸酶H",
  "RNase Inhibitor": "RNase Inhibitor",
  "RNase T1": "核糖核酸酶T1",
  "RSC 2.0 modification": "RSC 2.0修饰",
  "RiboGalSTAR™": "RiboGalSTAR™",
  "Ribonuclease T1": "核糖核酸酶T1",
  "Roche Custom Biotech": "罗氏定制生物技术",
  "SBIA": "SBIA",
  "SBS": "SBS",
  "SMART Digest RNase T1 kit": "SMART Digest RNase T1试剂盒",
  "SPOS": "固相合成（SPOS）",
  "ST Pharm": "ST Pharm",
  "STP122G": "STP122G",
  "SUGAR-TARGET glycosyl-transferase cascade": "SUGAR-TARGET糖基转移酶级联反应",
  "Sangon Biotech": "生工",
  "SiaT": "SiaT",
  "Snake Venom Phosphodiesterase": "蛇毒磷酸二酯酶",
  "Sollbruchstellen": "易断位点",
  "SpyCatcher/SpyTag": "SpyCatcher/SpyTag",
  "Strain-Promoted Azide–Alkyne Cycloaddition": "应变促进叠氮–炔烃环加成",
  "Supply-Chain Opportunity Map": "供应链机会地图",
  "Suzhou Taike": "苏州泰科",
  "Synthesis Modality": "合成模式",
  "T4 RNA Ligase 1": "T4 RNA连接酶1",
  "T4 RNA Ligase 2": "T4 RNA连接酶2",
  "T7 RNA polymerase": "T7 RNA聚合酶",
  "TRL": "技术成熟度",
  "TRiM™": "TRiM™平台",
  "Takara Bio": "宝生物工程",
  "Technical Guidelines for Pharmaceutical Research on Chemically Synthesized Oligonucleotide Drugs (Innovative Drugs)": "化学合成寡核苷酸药物（创新药）药学研究技术指导原则（试行）",
  "Terminal Deoxynucleotidyl Transferase": "末端脱氧核苷酸转移酶",
  "Tianjin Orilife": "天津奥利法",
  "Tier 1": "第一层级",
  "Tier 2": "第二层级",
  "Tier 3": "第三层级",
  "Triazole linker": "三唑接头",
  "TrisGal-6 scaffold": "TrisGal-6骨架",
  "UDP-Gal": "UDP-Gal",
  "UDP-GalNAc": "UDP-GalNAc",
  "Unylinker-functionalized polystyrene support": "Unylinker功能化聚苯乙烯载体",
  "Vazyme": "诺唯赞",
  "Worthington Biochemical": "Worthington Biochemical",
  "WuXi AppTec": "药明康德",
  "Wuhu Huaren": "芜湖华仁",
  "XBP-1": "XBP-1",
  "Yeasen Biotech": "翌圣生物科技",
  "acceptable daily intake": "每日可接受摄入量",
  "activated-intermediate shelf life": "活化中间体货架期",
  "anion-exchange polishing": "阴离子交换精制",
  "antisolvent": "反溶剂",
  "arm-coupling reaction": "臂偶联反应",
  "atom-economy penalty": "原子经济性损失",
  "avidity plateau": "亲合力平台",
  "bead attrition": "微珠磨损",
  "bottom-up mapping": "自下而上图谱分析",
  "branching-point coupling": "分支点偶联",
  "bundled enzyme-carrier product": "酶-载体捆绑产品",
  "cardiometabolic disease": "心脏代谢疾病",
  "cell-free synthesis": "无细胞合成",
  "channeling": "沟流",
  "charge-state deconvolution": "电荷态反卷积",
  "chemoenzymatic": "化学酶法",
  "choline chloride/glycerol": "氯化胆碱/甘油",
  "choline chloride/urea (reline)": "氯化胆碱/尿素（reline）",
  "class extension": "品类延伸",
  "clinical translation": "临床转化",
  "cluster-arm variants": "簇臂变体",
  "co-dosing program": "联合给药项目",
  "cocktail formulation": "鸡尾酒制剂",
  "complement dysregulation": "补体失调",
  "continuous process verification": "连续工艺验证",
  "continuous-flow microgel reactor": "连续流微凝胶反应器",
  "control threshold": "控制阈值",
  "convergent assembly": "汇聚式组装",
  "copper scavenging": "铜清除",
  "copper-residue burden": "铜残留合规负担",
  "coronary heart disease": "冠心病",
  "covalently-linked tandem siRNA": "共价连接串联siRNA",
  "cross-activity": "交叉活性",
  "denaturing IP-RP-LC-MS": "变性离子对反相液相色谱-质谱",
  "dendritic scaffold": "树枝状骨架",
  "design paradigm": "设计范式",
  "di-valent branched construct": "二价分支构建体",
  "diamine scaffold": "二胺骨架",
  "disulfide bond": "二硫键",
  "domestic-substitution feasibility": "国产替代可行性",
  "droplet microfluidics": "液滴微流控技术",
  "dsRNA": "dsRNA",
  "dual-functional RNAi therapeutic": "双功能RNAi治疗药物",
  "enantiomeric excess": "对映体过量值",
  "enzymatic-ligation": "酶连接",
  "enzyme loading per gram": "每克载体酶载量",
  "fixed-bed copper-scavenging resin": "固定床铜清除树脂",
  "glutaraldehyde": "戊二醛",
  "glycosyl-transferase": "糖基转移酶",
  "hepatic parenchymal clearance": "肝实质清除率",
  "hetero-duplex": "异源双链体",
  "hexaethyleneglycol": "六乙二醇",
  "hexavalent GalNAc cluster": "六价GalNAc簇",
  "high-load polymeric support": "高载量聚合物载体",
  "homo-duplex": "同源双链体",
  "hypertriglyceridemia": "高甘油三酯血症",
  "immobilized enzyme": "固定化酶",
  "immobilized polymerase/phosphatase reactor": "固定化聚合酶/磷酸酶反应器",
  "inline conversion monitoring": "在线转化率监测",
  "inter-lot specific activity variation": "批间比活力变异",
  "junction-verification assay": "连接位点验证检测",
  "lenticular beads": "扁豆形微珠",
  "lipid nanoparticle": "脂质纳米颗粒",
  "liquid-phase oligonucleotide synthesis": "液相寡核苷酸合成",
  "liquid-phase synthesis": "液相合成",
  "mRNAi GOLD™": "mRNAi GOLD™",
  "maleimide-activated agarose": "马来酰亚胺活化琼脂糖",
  "manufacturing stack": "制造体系",
  "material diversion strategy": "物料转移策略",
  "membrane bioreactor": "膜生物反应器",
  "methacrylate copolymer beads": "甲基丙烯酸酯共聚物微珠",
  "mixed hyperlipidemia": "混合型高脂血症",
  "monoantennary GalNAc": "单天线GalNAc",
  "monomer diversity index": "单体多样性指标",
  "muRNA": "muRNA",
  "multivalent GalNAc cluster": "多价GalNAc簇",
  "multivalent GalNAc scaffold": "多价GalNAc骨架",
  "murine TdT": "鼠源TdT",
  "mxRNA": "mxRNA",
  "neurodegeneration": "神经退行性疾病",
  "nonclinical guidance": "非临床指南",
  "nuclease mapping": "核酸酶图谱分析",
  "packed-bed reactor": "填充床反应器",
  "partially conjugated strand": "部分偶联链",
  "particle-integrity monitoring": "颗粒完整性监测",
  "pentavalent GalNAc": "五价GalNAc",
  "phosphoramidite monomer": "亚磷酰胺单体",
  "pipeline inflation": "管线虚胖",
  "platform-multiplication event": "平台倍增事件",
  "polymer microgels": "聚合物微凝胶",
  "pre-validated package": "预验证文件包",
  "pressure-drop effects": "压降效应",
  "process debt": "工艺债务",
  "process node": "工艺节点",
  "process signature": "工艺特征",
  "product-specific guidance": "产品专项指南",
  "protecting-group strategy": "保护基策略",
  "protective allele": "保护性等位基因",
  "pyranose": "吡喃糖",
  "qualification barrier": "资质壁垒",
  "rSAP": "rSAP",
  "ratio QC": "比例质控",
  "receptor-mediated uptake": "受体内吞",
  "regulatory vector": "监管向量",
  "release-profile QC": "释放谱质控",
  "residual enzyme surveillance": "残留酶监控",
  "ribofuranose scaffold": "核糖呋喃糖骨架",
  "serially assembled trivalent construct": "序贯组装三价构建体",
  "siRELIS facility": "siRELIS工厂",
  "silica bead fines": "硅胶微珠细粉",
  "solid-phase phosphoramidite synthesis": "固相亚磷酰胺合成",
  "solid-phase synthesis": "固相合成",
  "soluble anchor": "可溶性锚定基团",
  "spacer accessibility": "间隔臂可及性",
  "splint removal": "DNA夹板去除",
  "streptavidin-coated silica beads": "链霉亲和素包被硅胶微珠",
  "structure-activity study": "构效关系研究",
  "sub-saturation binding regime": "未饱和结合区间",
  "supplier concentration": "供应商集中度",
  "swelling index": "溶胀指数",
  "tetraantennary": "四天线",
  "tetraloop": "四环体",
  "top-down intact-mass sequencing": "自上而下完整质量测序",
  "toxicokinetic subfactor justification": "毒代动力学亚因子论证",
  "triantennary GalNAc": "三天线GalNAc",
  "truncated cluster impurity": "截短型簇杂质"
}